Ndegeocello has worked with The Rolling Stones, Prince, Madonna, Chaka Khan, Terrence Blanchard and Cassandra Wilson. She has also collaborated with Billy Preston, John Mellencamp, Missy “Misdemeanor” Elliott, Redman, Lizz Wright, Lalah Hathaway, Zap Mama, Cody Chestnut, Toshi Reagon, and many others.
In 2016, Ndegeocello began work with Charlotte Brathwaite, Staceyann Chin, and other collaborators, to create The Gospel of James Baldwin, an evolving work of music theater inspired by The Fire Next Time (1963), Baldwin’s polemic about race in America.